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| Date : 9/25/2008 |
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Hour : 5:11:04 PM |
| Resource : Reuters |
| Summery : Delivering flu vaccines straight into the lungs instead of through routine injections could trigger a far stronger immune response, a study has found.
The world is expected to be extremely short of vaccines in the event of a flu pandemic, so the search for the best way to deliver vaccines is important because it would economize on the quantity of each dose.
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The Australian study, published in Mucosal Immunology, showed that lower doses of a seasonal flu vaccine delivered into the lungs of sheep gave better protection against flu than a higher standard dose that was injected into another group of sheep.
"Our results suggest that delivery by the lung may allow a much lower ... dose to be used in the influenza vaccine, while inducing equivalent or perhaps even improved protection. This would mean more people would quickly be able to receive the vaccine," associate professor Philip Sutton of the Center for Animal Biotechnology at the University of Melbourne wrote in an email to Reuters.
The scientists delivered three different doses of flu vaccines (15, 5 and 1 micrograms) into the lungs of three groups of sheep using a bronchoscope, or tube. A fourth group of sheep was injected with standard 15-microgram flu vaccines.
*** Read more at : http://news.yahoo.com/s/nm/20080925/hl_nm/us_influenza_vaccine_lungs
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